Users that proudly espouse transphobic rhetoric should be reported. Some cases are more open and shut than others.
The following are examples that are by themselves enough to warrant a report:
Example.
If multiple tweets paint a picture together, report them all (you can report multiple tweets for a single account.)
Be careful when reporting a user based on a single tweet. If you're not sure, right-click on their
name and select Soupcan -> Search tweets... to bring up more examples that might be
better to report someone for.
There are situations where just going off a single tweet is invalid:
A bio by itself can be sufficient for a report, if they are a self-declared TERF, and/or use transphobic
symbols or abbreviations such as LGB minus TQ, or any of the same reasons you can report a tweet for.
In the reason box, just write Bio: and copy and paste their entire bio into the field.
The default is to link the tweet and add the tweet text in. If there is an image attached, briefly describe it (if it contributes to the report.) This is sufficient unless you need to add more context, such as in this case where what it is responding to is important for the full picture.
Example.
How I add context.